Article published April 3rd, 2017
Researchers from Birmingham University in the UK have developed an interesting alternative to using antibiotics for a certain rare lung disease that can be caused by several bacterium including P. aeruginosa. They would run a similar process to dialysis, called plasmapheresis, but instead of removing waste from the blood they would remove a certain antibody from the blood that was in excess, which prevented them from fighting the infecting bacterium. They would run this several times a week, replacing antibodies via blood transfusions, and this reduced hospitalization time and reduced the effects of it significantly, all without antibiotics. Research is being done to see if this is a viable replacement to some antibiotic treatments.
This relates to class material because we covered usage of antibiotics and how to prevent resistance. This would be a very good way to eliminate adding resistance to bacterium that can be fought this way significantly by not even using antibiotics.
I thought it was interesting how they are trying to find ways to avoid antibiotics completely, which would significantly decrease the worry of antibiotic resistance. It is a fairly new treatment, but it looks very plausible and accurate based on the reasoning in the article. It is fairly simplified for the public but is in depth enough so that the treatment process can be understood.
One question I would ask is how this could be expanded upon to more diseases beyond just filtering out antibodies from the blood. Could this be applied to other immune response diseases? People who are immune suppressed?